The rhodococcal cell envelope: composition, organisation and biosynthesis

Sutcliffe, Iain, Brown, Alistair and Dover, Lynn (2010) The rhodococcal cell envelope: composition, organisation and biosynthesis. In: Biology of Rhodococcus. Microbiology Monographs, 16 . Springer, London, pp. 29-71. ISBN 978-3642129360

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Official URL: http://dx.doi.org/10.1007/978-3-642-12937-7_2

Abstract

The cell envelopes of i and their closest relatives are dominated by the presence of large branched chain fatty acids, the mycolic acids. Here we review the structural features underlying the incorporation of the mycolic acids into the rhodococcal cell envelope, notably their covalent anchoring to the peptidoglycan–arabinogalactan complex and their organisation into an outer lipid permeability barrier. Rhodococcal cell envelopes also accommodate diverse non-covalently associated components such as channel-forming porin proteins, free lipids, lipoglycans, lipoproteins and capsules or cell envelope polysaccharides. Based on the extensive studies of cell envelope biogenesis in corynebacteria and mycobacteria, we have used a comparative genomics approach to examine the pathways for the biosynthesis of the major cell envelope components of Rhodococcus jostii RHA1.

Item Type: Book Section
Additional Information: ISSN: 1862-5576
Uncontrolled Keywords: microbiological synthesis, peptidoglycans
Subjects: C500 Microbiology
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
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Depositing User: EPrints Services
Date Deposited: 29 Mar 2011 10:48
Last Modified: 10 Nov 2016 12:40
URI: http://nrl.northumbria.ac.uk/id/eprint/1397

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