The effect on cadaver blood DNA identification by the use of targeted and whole body post-mortem computed tomography angiography

Rutty, Guy, Barber, Jade, Amoroso, Jasmin, Morgan, Bruno and Graham, Eleanor (2013) The effect on cadaver blood DNA identification by the use of targeted and whole body post-mortem computed tomography angiography. Forensic Science Medicine and Pathology, 9 (4). pp. 489-495. ISSN 1556-2891

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Official URL: http://dx.doi.org/10.1007/s12024-013-9467-x

Abstract

Post-mortem computed tomography angiography (PMCTA) involves the injection of contrast agents. This could have both a dilution effect on biological fluid samples and could affect subsequent post-contrast analytical laboratory processes. We undertook a small sample study of 10 targeted and 10 whole body PMCTA cases to consider whether or not these two methods of PMCTA could affect post-PMCTA cadaver blood based DNA identification. We used standard methodology to examine DNA from blood samples obtained before and after the PMCTA procedure. We illustrate that neither of these PMCTA methods had an effect on the alleles called following short tandem repeat based DNA profiling, and therefore the ability to undertake post-PMCTA blood based DNA identification.

Item Type: Article
Uncontrolled Keywords: whole body, post-mortem, computed tomography, angiography, DNA
Subjects: F100 Chemistry
F400 Forensic and Archaeological Science
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: Nicola King
Date Deposited: 28 Nov 2013 10:56
Last Modified: 10 Aug 2015 11:30
URI: http://nrl.northumbria.ac.uk/id/eprint/14725

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