Corynephages: Infections of the Infectors

Sangal, Vartul and Hoskisson, Paul (2014) Corynephages: Infections of the Infectors. In: Corynebacterium diphtheriae and Related Toxigenic Species: Genomics, Pathogenicity and Applications. Springer, London, pp. 67-81. ISBN 978-9400776234

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Corynebacterium diphtheriae is the etiological agent of diphtheria; an acute toxin-mediated infection of the upper respiratory tract and skin. The toxin gene is encoded on a temperate bacteriophage, which during lysogeny is capable of toxin production. In this chapter, we will summarise current knowledge regarding corynephage, focusing on the lifecycle and biology of the toxin-carrying corynephages that are known to convert pathogenic corynebacteria, and discuss the insights recent genome corynebacterial sequencing has given us.

Item Type: Book Section
Uncontrolled Keywords: bacteriophage, toxin
Subjects: C400 Genetics
C500 Microbiology
Department: Faculties > Health and Life Sciences > Applied Sciences
Depositing User: Vartul Sangal
Date Deposited: 07 Jan 2014 09:11
Last Modified: 24 Oct 2017 11:25

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