Mechanism of thioamide drug action against tuberculosis and leprosy

Wang, Feng, Dover, Lynn, Gulten, Gulcin, Langley, Robert, Besra, Gurdyal, Jacobs, William and Sacchettini, James (2007) Mechanism of thioamide drug action against tuberculosis and leprosy. Journal of Experimental Medicine, 204 (1). pp. 73-78. ISSN 0022-1007

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Official URL: http://dx.doi.org/10.1084/jem.20062100

Abstract

Dover developed molecular constructs and the initial in viro data that initiated a structural biology route to the determination of the mode of action of the important anti-TB agent ethionamide used to treat multi-drug resistant infections and its analogue prothionamide used to treat leprosy.

Item Type: Article
Subjects: B200 Pharmacology, Toxicology and Pharmacy
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: EPrint Services
Date Deposited: 18 Dec 2008 15:18
Last Modified: 08 May 2017 12:28
URI: http://nrl.northumbria.ac.uk/id/eprint/1645

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