Revolutionizing Prokaryotic Systematics Through Next-Generation Sequencing

Sangal, Vartul, Nieminen, Leena, Tucker, Nicholas and Hoskisson, Paul (2014) Revolutionizing Prokaryotic Systematics Through Next-Generation Sequencing. In: New Approaches to Prokaryotic Systematics. Methods in Microbiology, 41 . Elsevier, London, pp. 75-101. ISBN 9780128001769

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Official URL: http://dx.doi.org/10.1016/bs.mim.2014.07.001

Abstract

Next-generation sequencing has revolutionized modern research in all life sciences. It has been applied in studying evolution, global transmission and local adaptation of pathogens, microbial ecology, genetics and physiology. In this chapter, we have provided a brief summary of recent advances in sequencing technologies and easy to use bioinformatic tools to analyse sequence data, with a focus on prokaryotic biology. We have emphasized the importance of routinely applying whole genome sequencing in prokaryotic systematics, evolution, genotyping and functional characterization.

Item Type: Book Section
Uncontrolled Keywords: mapping, SNP analyses, phylogenetic analyses, prokaryotic systematics
Subjects: C500 Microbiology
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: Ay Okpokam
Date Deposited: 05 Jan 2015 11:09
Last Modified: 02 Oct 2015 16:15
URI: http://nrl.northumbria.ac.uk/id/eprint/18557

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