Solid-phase microextraction as a method for estimating the octanol-water partition coefficient

Dean, John, Tomlinson, William, Makovskaya, Valeria Vladimirovna, Cumming, Robert, Hetheridge, Malcolm and Comber, Michael (1996) Solid-phase microextraction as a method for estimating the octanol-water partition coefficient. Analytical Chemistry, 68 (1). pp. 130-133. ISSN 0003-2700

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Official URL: http://dx.doi.org/ 10.1021/ac950778g

Abstract

The determination of octanol-water partition coefficients (log KOW) is important for the prediction of the fate of organic pollutants in the environment. Traditionally, log KOW values are determined by shake-flask, estimated by, e.g., HPLC retention data, or calculated, e.g., from ClogP. In this paper, an alternative approach is reported that allows log KOW, to be estimated from solid-phase microextraction (SPME) data. Previously reported attempts to correlate SPME data with log KOW are discussed. The results obtained in this work for six phenols, using an 85 μm polyacrylate-coated fiber, indicate that SPME is a viable method for estimating log KOW values <3.5.

Item Type: Article
Subjects: F100 Chemistry
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 18 Feb 2015 11:08
Last Modified: 10 Aug 2015 11:53
URI: http://nrl.northumbria.ac.uk/id/eprint/18585

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