Fused Pyridine Derivatives from the Wittig Reaction of some Fluorinated Amides

Latham, Elliot, Murphy, Steven and Stanforth, Stephen (1995) Fused Pyridine Derivatives from the Wittig Reaction of some Fluorinated Amides. Tetrahedron, 51 (37). pp. 10385-10388. ISSN 0040 4020

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Official URL: http://dx.doi.org/10.1016/0040-4020(95)00605-8

Abstract

Compound 2 reacted with phosphorane 3 (R = Et) giving the quinoline derivative 5 whereas thiophenes 7 and 9 gave enamines 8 and 10 respectively with the appropriate phosphorane 3 (R = Me or Et). Pyridine derivative 11 yielded only ethyl 2-aminonicotinate with phosphorane 3 (R = Et). Compounds 8 and 10 gave the fused pyridine derivatives 14 and 15 respectively when treated with sodium hydride.

Item Type: Article
Subjects: F100 Chemistry
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 17 Feb 2015 15:52
Last Modified: 10 Aug 2015 11:53
URI: http://nrl.northumbria.ac.uk/id/eprint/18734

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