Estimation and determination of steroid solubility in supercritical carbon dioxide

Dean, John, Kane, Mark, Khundker, Sharmin, Dowle, Christopher, Tranter, Roy and Jones, Peter (1995) Estimation and determination of steroid solubility in supercritical carbon dioxide. The Analyst, 120 (8). pp. 2153-2157. ISSN 0003 2654

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Official URL: http://dx.doi.org/10.1039/an9952002153

Abstract

The solubility of ten steroids in supercritical carbon dioxide is reported over a range of temperatures (35-100 °C) and pressures (84-231 kg cm -2). The solubility of testosterone, determined in this work, compares favourably with solubility data previously reported. The use of the solubility parameter and a hydrophobicity term (log P), has been shown to provide a qualitative estimate of steroid solubility.

Item Type: Article
Uncontrolled Keywords: Hydrophobicity, Log P, solubility parameter, solubility prediction, steroid solubility, supercritical carbon dioxide
Subjects: F100 Chemistry
Department: Faculties > Health and Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 17 Feb 2015 15:54
Last Modified: 24 Oct 2017 11:28
URI: http://nrl.northumbria.ac.uk/id/eprint/18735

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