A Surface Acoustic Wave-Based Immunosensing Device Using a Nanocrystalline ZnO Film on Si

Lee, Dae-Sik, Lee, Jun Hwang, Luo, Jikui, Fu, Yong Qing, Milne, William, Maeng, Sunglyul, Jung, Mun Yeon, Park, Sun Hee and Yoon, Hyun (2009) A Surface Acoustic Wave-Based Immunosensing Device Using a Nanocrystalline ZnO Film on Si. Journal of Nanoscience and Nanotechnology, 9 (12). pp. 7181-7185. ISSN 1533 4880

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Official URL: http://dx.doi.org/10.1166/jnn.2009.1662

Abstract

The novelty of this study resides in the fabrication of a bio-sensing device, based on the surface acoustic wave (SAW) on a nanocrystalline ZnO film. The ZnO film was deposited using an rf magnetron sputtering at room temperature on silicon. The deposited films showed the c-axis-oriented crystallite with grain size of ∼40 nm. The immunosensing device was fabricated using photolithographic protocols on the film. As a model biomolecular recognition and immunosensing, biospecific interaction between a 6-(2,4-dinitrophenyl)aminohexanoic acid (DNP) antigen and its antibody was employed, demonstrating the shifts of resonant frequencies on SAW immunosensing device. The device exhibited a linearity as a function of the antibody concentration in the range of 20∼20,000 ng/ml.

Item Type: Article
Uncontrolled Keywords: DNP, immunosensing, nanocrystalline ZNO, SAW, ZNO/SI
Subjects: F200 Materials Science
Department: Faculties > Engineering and Environment > Physics and Electrical Engineering
Depositing User: Becky Skoyles
Date Deposited: 23 Mar 2015 09:51
Last Modified: 10 Aug 2015 11:25
URI: http://nrl.northumbria.ac.uk/id/eprint/21660

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