Efficacy of intracameral and subconjunctival cefuroxime in preventing endophthalmitis after cataract surgery

Yu-Wai-Man, Patrick, Morgan, Stephen, Hildreth, Anthony, Steel, David and Allen, David (2008) Efficacy of intracameral and subconjunctival cefuroxime in preventing endophthalmitis after cataract surgery. Journal of Cataract and Refractive Surgery, 34 (3). pp. 447-451. ISSN 0886-3350

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Official URL: http://dx.doi.org/10.1016/j.jcrs.2007.10.041

Abstract

Purpose
To compare the efficacy of intracameral cefuroxime versus subconjunctival cefuroxime in reducing the rate of endophthalmitis after cataract surgery.
Setting
Single-specialty eye hospital, Sunderland, United Kingdom.
Methods
A retrospective analysis of all presumed infectious endophthalmitis cases from January 1, 2000, to December 31, 2006 was performed. The rate of presumed infectious endophthalmitis in patients receiving subconjunctival cefuroxime was compared with those receiving intracameral cefuroxime at the end of surgery.
Results
This study included 36743 phacoemulsification cataract procedures. The mean rate of presumed infectious endophthalmitis was 0.95 per 1000 cases. The incidence of endophthalmitis was higher in the subconjunctival cefuroxime group than in the intracameral cefuroxime group; the difference was statistically significant with an odds ratio of 3.01 (95% confidence interval, 1.37-6.63). Conclusion Intracameral cefuroxime was a safe alternative to subconjunctival cefuroxime and led to a lower rate of endophthalmitis

Item Type: Article
Subjects: A300 Clinical Medicine
Department: Faculties > Health and Life Sciences > School of Health, Community and Education Studies > Public Health and Wellbeing
Depositing User: EPrints Services
Date Deposited: 12 Aug 2009 11:50
Last Modified: 10 Aug 2015 11:43
URI: http://nrl.northumbria.ac.uk/id/eprint/2454

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