A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides

Vincetti, Paolo, Brianza, Anna, Scalacci, Nicolò, Costantino, Gabriele, Castagnolo, Daniele and Radi, Marco (2016) A microwave-assisted multicomponent protocol for the synthesis of benzofuran-2-carboxamides. Tetrahedron Letters, 57 (13). pp. 1464-1467. ISSN 0040-4039

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Official URL: http://dx.doi.org/10.1016/j.tetlet.2016.02.068

Abstract

A fast, versatile and practical microwave-assisted multicomponent protocol for the synthesis of substituted benzofuran-2-carboxamides has been developed. The present method proved to be effective on a series of commercially available amines, 2′-hydroxyacetophenones, aldehydes, and benzonitriles and could be exploited in drug-discovery campaigns for the rapid identification of biologically active hit compounds.

Item Type: Article
Uncontrolled Keywords: Multicomponent reaction; Benzofuran; Microwave; Combinatorial chemistry
Subjects: F100 Chemistry
Department: Faculties > Health and Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 16 Mar 2016 13:35
Last Modified: 24 Oct 2017 11:23
URI: http://nrl.northumbria.ac.uk/id/eprint/26365

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