Detection of exogenous VOCs as a novel in vitro diagnostic technique for the detection of pathogenic bacteria

Lough, Fraser, Perry, John, Stanforth, Stephen and Dean, John (2017) Detection of exogenous VOCs as a novel in vitro diagnostic technique for the detection of pathogenic bacteria. TrAC Trends in Analytical Chemistry, 87. pp. 71-81. ISSN 0165-9936

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Official URL: http://dx.doi.org/10.1016/j.trac.2016.12.004

Abstract

The evolution of volatile organic compounds (VOCs) provides an opportunistic approach for the detection of pathogenic bacteria. This approach can be enhanced by the application of VOC-labelled enzyme substrates that target specific enzyme activities of the bacteria under investigation. Detection of the VOCs provides a novel, specific and sensitive approach for the detection of pathogenic bacteria. This review highlights the importance of this approach alongside a range of alternative detection techniques for the identification of pathogenic bacteria.

Item Type: Article
Uncontrolled Keywords: Volatile organic compounds; Detection; Enzymes; Markers; Diseases
Subjects: C500 Microbiology
F100 Chemistry
Department: Faculties > Health and Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 09 Jan 2017 14:09
Last Modified: 25 Oct 2017 15:55
URI: http://nrl.northumbria.ac.uk/id/eprint/29085

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