Vitamin D: Implications for ocular disease and therapeutic potential

Reins, Rose and McDermott, Alison (2015) Vitamin D: Implications for ocular disease and therapeutic potential. Experimental Eye Research, 134. pp. 101-110. ISSN 0014-4835

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Official URL: https://doi.org/10.1016/j.exer.2015.02.019

Abstract

Vitamin D is a multifunctional hormone that is now known to play a significant role in a variety of biological functions in addition to its traditional role in regulating calcium homeostasis. There are a large number of studies demonstrating that adequate vitamin D levels are important in maintaining health and show that vitamin D is able to be utilized at local tissue sites. In the eye, we have increasing evidence of the association between disease and vitamin D. In this narrative review, we summarize recent findings on vitamin D and its relationship to various ocular pathologies and the therapeutic potential for some of these, as well as examine the basic science studies that demonstrate that vitamin D is biologically relevant in the eye.

Item Type: Article
Uncontrolled Keywords: Vitamin D; Ocular disease; Deficiency; Anti-inflammatory; Genetic variations
Subjects: B500 Ophthalmics
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 23 May 2017 10:15
Last Modified: 23 May 2017 10:15
URI: http://nrl.northumbria.ac.uk/id/eprint/30794

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