Design and Optimisation of a Microgripper: Demonstration of Biomedical Applications Using the Manipulation of Oocytes

Solano, B. P., Gallant, Andrew and Wood, David (2009) Design and Optimisation of a Microgripper: Demonstration of Biomedical Applications Using the Manipulation of Oocytes. In: Design, Test, Integration & Packaging of MEMS/MOEMS, 2009. MEMS/MOEMS '09. Symposium on. IEEE, pp. 61-65. ISBN 978-1-4244-3874-7

Full text not available from this repository. (Request a copy)

Abstract

We present a bidirectional electrothermal microgripper for the advanced manipulation of single large cells. The device demonstrates excellent performance, and shows great potential as a supporting microtool for different biomedical procedures such as oocyte selection or electrofusion of cells. In particular, we focus on the operation of the device in real environments, i.e. integrated in a standard biological micromanipulation station and entirely submerged in a biological fluid, for the handling and transportation of ‘live’ specimens (in our case mice oocytes). A clamping mechanism is included in the design that limits the pressure exerted over the biological specimen to an approximate maximum of 40 μN, whilst maintaining a robust grip, with a force up to 300 μN, between the arms of the microgripper.

Item Type:	Book Section
Subjects:	H900 Others in Engineering
Department:	Faculties > Engineering and Environment > Geography and Environmental Sciences
Depositing User:	Becky Skoyles
Date Deposited:	17 Apr 2018 10:18
Last Modified:	11 Oct 2019 21:05
URI:	http://nrl.northumbria.ac.uk/id/eprint/33993

Downloads