Cardiopulmonary exercise testing predicts postoperative outcome in patients undergoing gastric bypass surgery

Hennis, Philip, Meale, Paula, Hurst, Rachel, O’Doherty, Alasdair, Otto, James, Kuper, M., Harper, N., Sufi, P.A., Garway-Heath, David, Montgomery, Hugh and Grocott, Michael (2012) Cardiopulmonary exercise testing predicts postoperative outcome in patients undergoing gastric bypass surgery. British Journal of Anaesthesia, 109 (4). pp. 566-571. ISSN 0007-0912

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1093/bja/aes225

Abstract

BACKGROUND: For several types of non-cardiac surgery, the cardiopulmonary exercise testing (CPET)-derived variables anaerobic threshold (AT), peak oxygen consumption (VO2 peak), and ventilatory equivalent for CO(2) (VE/VCO2 ) are predictive of increased postoperative risk: less physically fit patients having a greater risk of adverse outcome. We investigated this relationship in patients undergoing gastric bypass surgery.

METHODS: All patients (<190 kg) who were referred for CPET and underwent elective gastric bypass surgery at the Whittington Hospital NHS Trust between September 1, 2009, and February 25, 2011, were included in the study (n=121). Fifteen patients did not complete CPET. CPET variables (VO2 peak, AT, and VE/VCO2 ) were derived for 106 patients. The primary outcome variables were day 5 morbidity and hospital length of stay (LOS). The independent t-test and Fisher's exact test were used to test for differences between surgical outcome groups. The predictive capacity of CPET markers was determined using receiver operating characteristic (ROC) curves.

RESULTS: The AT was lower in patients with postoperative complications than in those without [9.9 (1.5) vs 11.1 (1.7) ml kg(-1) min(-1), P=0.049] and in patients with a LOS>3 days compared with LOS ≤ 3 days [10.4 (1.4) vs 11.3 (1.8) ml kg(-1) min(-1), P=0.023]. ROC curve analysis identified AT as a significant predictor of LOS>3 days (AUC 0.640, P=0.030). The VO2 peak and VE/VCO2 were not associated with postoperative outcome.

CONCLUSIONS: AT, determined using CPET, predicts LOS after gastric bypass surgery.

Item Type: Article
Uncontrolled Keywords: AT, determined using CPET, predicts LOS after gastric bypass surgery
Subjects: A300 Clinical Medicine
C600 Sports Science
Department: Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: Paul Burns
Date Deposited: 23 May 2018 11:16
Last Modified: 23 May 2018 11:16
URI: http://nrl.northumbria.ac.uk/id/eprint/34337

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