Tailored supramolecular gel and microemulsion crystallization strategies – is isoniazid really monomorphic?

Kennedy, Stuart, Jones, Christopher, Yufit, Dmitry, Nicholson, Kate, Cooper, Sharon and Steed, Jonathan (2018) Tailored supramolecular gel and microemulsion crystallization strategies – is isoniazid really monomorphic? CrystEngComm, 20 (10). pp. 1390-1398. ISSN 1466-8033

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Official URL: http://dx.doi.org/10.1039/C8CE00066B

Abstract

We report the application of supramolecular gel and microemulsion droplet crystallisation methodologies to isoniazid crystallization. Tailored gelators have been designed with isoniazid mimetic functionality in an attempt to control crystal morphology and polymorphic behaviour. Microemulsion crystallisation was investigated to achieve thermodynamic control over drug crystallisation. Both techniques resulted in only a single form of isoniazid implying that it is genuinely monomorphic.

Item Type: Article
Subjects: F100 Chemistry
Department: Faculties > Health and Life Sciences > Applied Sciences
Depositing User: Becky Skoyles
Date Deposited: 24 May 2018 11:41
Last Modified: 24 May 2018 11:41
URI: http://nrl.northumbria.ac.uk/id/eprint/34359

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