rTMS evidence for a dissociation in short-term memory for spoken words and nonwords

Savill, Nicola J., Cornelissen, Piers, Pahor, Anja and Jefferies, Elizabeth (2019) rTMS evidence for a dissociation in short-term memory for spoken words and nonwords. Cortex, 112. pp. 5-22. ISSN 0010-9452

[img]
Preview
Text
Savill et al - rTMS evidence for a dissociation in short-term memory for spoken words and nonwords AAM.pdf - Accepted Version
Available under License Creative Commons Attribution Non-commercial No Derivatives 4.0.

Download (1MB) | Preview
Official URL: https://doi.org/10.1016/j.cortex.2018.07.021

Abstract

Differing patterns of verbal short-term memory (STM) impairment have provided unique insights into the relationship between STM and broader language function. Lexicality effects (i.e., better recall for words than nonwords) are larger in patients with phonological deficits following left temporoparietal lesions, and smaller in patients with semantic impairment and anterior temporal damage, supporting linguistic accounts of STM. However, interpretation of these patient dissociations are complicated by (i) non-focal damage and (ii) confounding factors and secondary impairments. This study addressed these issues by examining the impact of inhibitory transcranial magnetic stimulation (TMS) on auditory-verbal STM performance in healthy individuals. We compared the effects of TMS to left anterior supramarginal gyrus (SMG) and left anterior middle temporal gyrus (ATL) on STM for lists of nonwords and random words. SMG stimulation disrupted nonword recall, in a pattern analogous to that observed in patients, compatible with a role for this site in processing speech sounds without support from long-term lexical-semantic representations. Stimulation of ATL, a semantic site, disrupted the recall of words but not nonwords. A visual pattern memory task indicated that these effects of TMS were restricted to the verbal domain. These data provide convergent evidence for the conclusions of neuropsychological studies that support linguistic accounts of verbal STM.

Item Type: Article
Uncontrolled Keywords: TMS; Verbal short-term memory; Semantic; Supramarginal gyrus; Anterior temporal lobe
Subjects: C800 Psychology
Department: Faculties > Health and Life Sciences > Psychology
Depositing User: Paul Burns
Date Deposited: 30 Aug 2018 13:57
Last Modified: 11 Oct 2019 10:23
URI: http://nrl.northumbria.ac.uk/id/eprint/35526

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics


Policies: NRL Policies | NRL University Deposit Policy | NRL Deposit Licence