Continuous computation in engineered gene circuits

Goñi-Moreno, Angel and Amos, Martyn (2012) Continuous computation in engineered gene circuits. Biosystems, 109 (1). pp. 52-56. ISSN 0303-2647

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Official URL: http://dx.doi.org/10.1016/j.biosystems.2012.02.001

Abstract

In this paper we consider the problem of representation and measurement in genetic circuits, and investigate how they can affect the reliability of engineered systems. We propose a design scheme, based on the notion of continuous computation, which addresses these issues. We illustrate the methodology by showing how a concept from computer architecture (namely, branch prediction) may be implemented in vivo, using a distributed approach. Simulation results confirm the in-principle feasibility of our method, and offer valuable insights into its future laboratory validation.

Item Type: Article
Uncontrolled Keywords: Branch prediction, Computer architecture, Synthetic biology
Subjects: C400 Genetics
C500 Microbiology
G400 Computer Science
Department: Faculties > Engineering and Environment > Computer and Information Sciences
Depositing User: Paul Burns
Date Deposited: 21 Feb 2019 18:11
Last Modified: 10 Oct 2019 23:18
URI: http://nrl.northumbria.ac.uk/id/eprint/38191

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