Characterisation of psu dic (6;5) (p21.3;q13) with reverse chromosome painting in a patient with secondary myelodysplastic syndrome following treatment for multiple myeloma

Lee-Jones, Lisa, Booth, Margaret, Ramsahoye, Bernard, Thompson, Peter, Whittaker, Jack and Hoy, Terry (2004) Characterisation of psu dic (6;5) (p21.3;q13) with reverse chromosome painting in a patient with secondary myelodysplastic syndrome following treatment for multiple myeloma. Cancer Genetics and Cytogenetics, 148 (1). pp. 49-54. ISSN 0165-4608

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Official URL: http://dx.doi.org/10.1016/S0165-4608(03)00218-8

Abstract

We report a case of a psu dic(6;5)(p21.3;q13) in a patient with secondary myelodysplastic syndrome (sMDS) following treatment for multiple myeloma. The abnormal chromosome was isolated by flow karyotyping and initially identified by reverse chromosome painting. The findings were then confirmed by forward painting. The value of flow karyotyping as a diagnostic technique in hematologic malignancies is discussed.

Item Type: Article
Additional Information: Lee-Jones devised and completed all laboratory aspects of the paper and wrote paper. Research was part of a larger study to develop new approaches to characterise complex cytogenetic abnormalities and identify cryptic rearrangements in neoplasia, to further our understanding of tumourigenesis.
Subjects: B900 Others in Subjects allied to Medicine
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: EPrints Services
Date Deposited: 23 Dec 2008 10:40
Last Modified: 10 Aug 2015 11:50
URI: http://nrl.northumbria.ac.uk/id/eprint/392

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