Cardiac structure and function characterized across age groups and between sexes in healthy wild-born captive chimpanzees (Pan troglodytes) living in sanctuaries

Drane, Aimee L., Atencia, Rebeca, Cooper, Stephen-Mark, Rodriguez, Pablo, Sanchez, Carlos, Simcox, Sarah, Feltrer, Yedra, Peck, Bruce, Eng, Jaclyn, Moittie, Sophie, Unwin, Steve, Howatson, Glyn, Oxborough, David, Stembridge, Mike R. and Shave, Rob E. (2019) Cardiac structure and function characterized across age groups and between sexes in healthy wild-born captive chimpanzees (Pan troglodytes) living in sanctuaries. American Journal of Veterinary Research, 80 (6). pp. 547-557. ISSN 0002-9645

Full text not available from this repository. (Request a copy)
Official URL: https://doi.org/10.2460/ajvr.80.6.547

Abstract

OBJECTIVE To comprehensively characterize cardiac structure and function, from infancy to adulthood, in male and female wild-born captive chimpanzees (Pan troglodytes) living in sanctuaries. ANIMALS 290 wild-born captive chimpanzees. PROCEDURES Physical and echocardiographic examinations were performed on anesthetized chimpanzees in 3 sanctuaries in Africa between October 2013 and May 2017. Results were evaluated across age groups and between sexes, and potential differences were assessed with multiple 1-way independent Kruskal-Wallis tests. RESULTS Results indicated that left ventricular diastolic and systolic function declined at a younger age in males than in females. Although differences in right ventricular diastolic function were not identified among age groups, right ventricular systolic function was lower in adult chimpanzees (> 12 years old), compared with subadult (8 to 12 years old) and juvenile (5 to 7 years old) chimpanzees. In addition, male subadult and adult chimpanzees had larger cardiac wall dimensions and chamber volumes than did their female counterparts. CONCLUSIONS AND CLINICAL RELEVANCE Results of the present study provided useful reference intervals for cardiac structure and function in captive chimpanzees categorized on the basis of age and sex; however, further research is warranted to examine isolated and combined impacts of blood pressure, age, body weight, and anesthetic agents on cardiac structure and function in chimpanzees.

Item Type: Article
Subjects: D200 Clinical Veterinary Medicine and Dentistry
Department: Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: Elena Carlaw
Date Deposited: 13 Jun 2019 13:37
Last Modified: 10 Oct 2019 18:02
URI: http://nrl.northumbria.ac.uk/id/eprint/39677

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics


Policies: NRL Policies | NRL University Deposit Policy | NRL Deposit Licence