The recent advances in the mathematical modelling of human pluripotent stem cells

Wadkin, L. E., Orozco-Fuentes, Sirio, Neganova, I., Lako, M., Shukurov, A. and Parker, N. G. (2020) The recent advances in the mathematical modelling of human pluripotent stem cells. SN Applied Sciences, 2 (2). p. 276. ISSN 2523-3963

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Official URL: https://doi.org/10.1007/s42452-020-2070-3

Abstract

Human pluripotent stem cells hold great promise for developments in regenerative medicine and drug design. The mathematical modelling of stem cells and their properties is necessary to understand and quantify key behaviours and develop non-invasive prognostic modelling tools to assist in the optimisation of laboratory experiments. Here, the recent advances in the mathematical modelling of hPSCs are discussed, including cell kinematics, cell proliferation and colony formation, and pluripotency and differentiation.

Item Type: Article
Uncontrolled Keywords: Mathematical modelling, Human pluripotent stem cells
Subjects: F300 Physics
G100 Mathematics
Department: Faculties > Engineering and Environment > Mathematics, Physics and Electrical Engineering
Depositing User: Rachel Branson
Date Deposited: 06 Apr 2020 12:55
Last Modified: 06 Apr 2020 13:00
URI: http://nrl.northumbria.ac.uk/id/eprint/42703

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