Surface free energy and microarray deposition technology

McHale, Glen (2007) Surface free energy and microarray deposition technology. Analyst, 132 (3). pp. 192-195. ISSN 0003-2654

[img]
Preview
PDF (Postprint)
Postprint_McHale_Analyst_vol_132_p192_2007.pdf - Published Version

Download (254kB) | Preview
Official URL: http://dx.doi.org/10.1039/b617339j

Abstract

Microarray techniques use a combinatorial approach to assess complex biochemical interactions. The fundamental goal is simultaneous, large-scale experimentation analogous to the automation achieved in the semiconductor industry. However, microarray deposition inherently involves liquids contacting solid substrates. Liquid droplet shapes are determined by surface and interfacial tension forces, and flows during drying. This article looks at how surface free energy and wetting considerations may influence the accuracy and reliability of spotted microarray experiments.

Item Type: Article
Uncontrolled Keywords: droplets, wetting, microarray,contact angle
Subjects: C100 Biology
F100 Chemistry
F300 Physics
Department: Faculties > Engineering and Environment > Mathematics, Physics and Electrical Engineering
Depositing User: Glen McHale
Date Deposited: 23 Aug 2012 11:58
Last Modified: 27 Oct 2017 05:05
URI: http://nrl.northumbria.ac.uk/id/eprint/8318

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics


Policies: NRL Policies | NRL University Deposit Policy | NRL Deposit Licence