Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumor immunity

Lipinski, Kai S., Todryk, Stephen, Mountain, Andrew, Pelech, Steven, Irvine, Alistair S., Kraaij, Robert, Bangma, Chris and Mills, Kingston (2006) Nitroreductase-based therapy of prostate cancer, enhanced by raising expression of heat shock protein 70, acts through increased anti-tumor immunity. Cancer Immunology Immunotherapy, 55 (3). pp. 347-354. ISSN 0340-7004

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Official URL: http://dx.doi.org/10.1007/s00262-005-0014-9
Item Type: Article
Additional Information: Supervisor investigating immunotherapy of tumours. Funded by Science Foundation Ireland in collaboration with Trinity College Dublin, ML Research (Biotech) and Kinexus Bioinformatics Corp., Canada. The study showed that killing tumour cells by “suicide gene therapy” induces stress proteins that increase anti-tumour immune responses and reduce or inhibit tumour growth in-vivo.
Subjects: A300 Clinical Medicine
Department: Faculties > Health and Life Sciences > School of Life Sciences > Applied Sciences
Depositing User: EPrint Services
Date Deposited: 08 Jan 2009 12:24
Last Modified: 27 Jun 2017 14:55
URI: http://nrl.northumbria.ac.uk/id/eprint/959

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