Botta, Maurizio, Castagnolo, Daniele, Pagano, Mafalda and Bernardini, Martina (2009) Domino alkylation-cyclization reaction of propargyl bromides with thioureas/thiopyrimidinones: A new facile synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones. Synlett, 2009 (13). pp. 2093-2096. ISSN 0936-5214
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Official URL: http://dx.doi.org/10.1055/s-0029-1217700
Abstract
A new synthesis of 2-aminothiazoles and 5H-thiazolo[3,2-a]pyrimidin-5-ones was developed as a domino alkylation-cyclization reaction of propargyl bromides with thioureas and thio¬pyrimidinones, respectively. Domino reactions were performed under microwave irradiation leading to desired compounds in a few minutes and high yields
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | domino reaction, 2-aminothiazole, thiazolopyrimidinone, microwave synthesis, antiviral agents |
| Subjects: | F100 Chemistry |
| Department: | Faculties > Health and Life Sciences > Applied Sciences |
| Depositing User: | Linda Barlow |
| Date Deposited: | 09 Jan 2013 10:31 |
| Last Modified: | 17 Dec 2023 14:02 |
| URI: | https://nrl.northumbria.ac.uk/id/eprint/10985 |
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