Impact of increasing doses of flavonoid-rich and flavonoid-poor fruits and vegetables on vascular reactivity in an ‘at risk’ group: findings from the FLAVURS study

George, Trevor, Chong, Mary Foong-Fong, Gordon, Michael, Minihane, Anne-Marie, Kennedy, Orla, Spencer, Jeremy and Lovegrove, Julie (2011) Impact of increasing doses of flavonoid-rich and flavonoid-poor fruits and vegetables on vascular reactivity in an ‘at risk’ group: findings from the FLAVURS study. Proceedings of the Nutrition Society, 70 (OCE4). E233. ISSN 0029-6651

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Abstract

CVD is responsible for 48% of all deaths each year in Europe. Endothelial cell dysfunction is key in early stage development of atherosclerosis leading to CVD. Vascular reactivity and arterial stiffness measured in vivo can be used as markers for general vascular dysfunction. Epidemiological studies indicate that diets rich in fruits and vegetables (F&V) are associated with reduced risk of CVD. However, the relationship between the type and amount of F&V consumed and CVD risk reduction has not been established. Increasing evidence suggests that dietary flavonoids may explain some of the CVD benefits of increased F&V intake. However, this hypothesis had not previously been tested in an adequately powered, dose-response dietary intervention trial.

Item Type:	Article
Subjects:	B400 Nutrition D600 Food and Beverage studies
Department:	Faculties > Health and Life Sciences > Applied Sciences
Depositing User:	Paul Burns
Date Deposited:	07 Nov 2014 10:30
Last Modified:	12 Oct 2019 18:26
URI:	http://nrl.northumbria.ac.uk/id/eprint/17983

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