Kane, Mark, Dean, John, Hitchen, Steven, Tomlinson, William, Tranter, Roy and Dowle, Christopher (1993) Quantitative structure-extraction relationships: A model for supercritical fluid extraction. Analyst, 118 (10). pp. 1261-1264. ISSN 0003-2654
Full text not available from this repository. (Request a copy)Abstract
A rapid method for predicting the solubility of an analyte in supercritical carbon dioxide is reported. The method is based on determining the hydrophobic interaction and the solubility parameter from easily obtained constants. The simplicity of the method is demonstrated with respect to a group of substituted benzophenones. Hydrophobicity is derived from log P values as determined by the Hansch-Leo method, whereas the solubility parameter is determined by the method of Fedors. Multilinear regression has indicated a direct correlation between the amount of analyte extracted, expressed as the mole fraction, and the log Pl solubility parameters.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | hydrophobicity, molecular structure, partition coefficient, solubility parameter, supercritical fluid extraction |
| Subjects: | F100 Chemistry |
| Department: | Faculties > Health and Life Sciences > Applied Sciences |
| Depositing User: | Becky Skoyles |
| Date Deposited: | 18 Feb 2015 09:46 |
| Last Modified: | 12 Oct 2019 17:29 |
| URI: | http://nrl.northumbria.ac.uk/id/eprint/18610 |
Actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
