Moving-part-free microfluidic systems for lab-on-a-chip

Luo, J. K., Fu, Yong Qing, Li, Yifan, Du, X.Y., Flewitt, Andrew, Walton, Anthony and Milne, William (2009) Moving-part-free microfluidic systems for lab-on-a-chip. Journal of Micromechanics and Microengineering, 19 (5). 054001. ISSN 0960-1317

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Abstract

Microfluidic systems are part of an emerging technology which deals with minute amounts of liquids (biological samples and reagents) on a small scale. They are fast, compact and can be made into a highly integrated system to deliver sample purification, separation, reaction, immobilization, labelling, as well as detection, thus are promising for applications such as lab-on-a-chip and handheld healthcare devices. Miniaturized micropumps typically consist of a moving-part component, such as a membrane structure, to deliver liquids, and are often unreliable, complicated in structure and difficult to be integrated with other control electronics circuits. The trend of new-generation micropumps is moving-part-free micropumps operated by advanced techniques, such as electrokinetic force, surface tension/energy, acoustic waves. This paper reviews the development and advances of relevant technologies, and introduces electrowetting-on-dielectrics and acoustic wave-based microfluidics. The programmable electrowetting micropump has been realized to dispense and manipulate droplets in 2D with up to 1000 addressable electrodes and electronics built underneath. The acoustic wave-based microfluidics can be used not only for pumping, mixing and droplet generation but also for biosensors, suitable for single-mechanism-based lab-on-a-chip applications.

Item Type:	Article
Subjects:	C900 Others in Biological Sciences F200 Materials Science F300 Physics H600 Electronic and Electrical Engineering
Department:	Faculties > Engineering and Environment > Mechanical and Construction Engineering
Depositing User:	Yifan Li
Date Deposited:	26 Feb 2015 12:28
Last Modified:	12 Oct 2019 22:55
URI:	http://nrl.northumbria.ac.uk/id/eprint/21244

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