The influence of tart cherry (Prunus cerasus, cv Montmorency) concentrate supplementation for 3 months on cardiometabolic risk factors in middle-aged adults: a randomised, placebo-controlled trial

Kimble, Rachel, Keane, Karen, Lodge, John and Howatson, Glyn (2021) The influence of tart cherry (Prunus cerasus, cv Montmorency) concentrate supplementation for 3 months on cardiometabolic risk factors in middle-aged adults: a randomised, placebo-controlled trial. Nutrients, 13 (5). p. 1417. ISSN 2072-6643

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Official URL: https://doi.org/10.3390/nu13051417

Abstract

Background: Tart Montmorency cherries (MC) have been shown to be rich in anthocyanins and other phytochemicals known to have anti-inflammatory properties and influence pathways that might improve cardiometabolic health. However, there is limited evidence for the longer-term use of tart cherries on these indices. The aim of the current study was to investigate the influence of MC concentrate on cardiometabolic health indices following a 3-month supplementation period. Methods: Fifty middle-aged adults (34 males and 16 females; mean ± SD age: 48 ± 6 years and BMI: 27.6 ± 3.7 kg/m2) completed a randomised, placebo-controlled parallel study in which they either received MC or an isocaloric placebo. Participants drank 30 ml of their allocated treatment twice per day for 3 months. Vascular function (blood pressure [BP], heart rate [HR], pulse wave velocity and analysis [PWV/A] and flow mediated dilation [FMD]) as well as indices of meta-bolic health (insulin, glucose, lipid profiles and high sensitivity C reactive protein) were measured following an overnight fast before and after the 3 months. Results: No effect of the intervention between groups was observed for vascular function or metabolic health variables following the intervention (P> 0.05). However, MC concentrate was shown to be safe and well tolerated and importantly did not have any deleterious effects on these outcomes. In conclusion MC has no in-fluence on cardiometabolic indices in middle-aged adults.

Item Type: Article
Additional Information: Funding information: This study was supported by Northumbria University and the Cherry Research Committee, a not-for-profit organisation, for a Collaborative Doctoral Research Studentship Scheme. The external funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Uncontrolled Keywords: tart cherry, cardiovascular disease, vascular function, metabolic health
Subjects: B900 Others in Subjects allied to Medicine
Department: Faculties > Health and Life Sciences > Applied Sciences
Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: John Coen
Date Deposited: 20 Apr 2021 09:22
Last Modified: 23 Apr 2021 09:00
URI: http://nrl.northumbria.ac.uk/id/eprint/45957

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