Au@Ag@Pt core-shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility

Qiu, Jiajun, Yang, Tingting, Li, Yifan, Qian, Wenhao and Liu, Xuanyong (2021) Au@Ag@Pt core-shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility. Rare Metals. ISSN 1001-0521 (In Press)

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Official URL: https://doi.org/10.1007/s12598-021-01799-w

Abstract

Although titanium and its alloys are extensively used in orthopedics and dentistry fields, implant failures still happen because of implant-associated infections. Herein, Au@Ag@Pt core–shell nanorods with noble metal combination were fabricated and assembled on medical titanium surface and the antibacterial activity and biocompatibility were investigated. The results showed that antibacterial rates of Ti–Au@Ag@Pt against S. epidermidis and P. aeruginosa were 89.7% and 92.7%, respectively. Besides, Ti–Au@Ag@Pt showed no obvious cell toxicity with MC3T3-E1 cells grew well on the sample surface. It was discovered that the Pt shell layer on Ti–Au@Ag@Pt slowed down the Ag ion release rate which endowed medical titanium surface with both antibacterial activity and good biocompatibility.

Item Type: Article
Additional Information: Funding information: This study was financially supported by the National Natural Science Foundation of China (No. 51831011), Shanghai Scientific and Technological Innovation Project (No. 20ZR1452200), the Program for Outstanding Medical Academic Leader (No. 2019LJ27), the PhD Research Startup Foundation of Jiamusi University (No. JMSUBZ2019-09), Shanghai Medical Key Specialty (No. ZK2019B12) and China Postdoctoral Science Foundation (No. 2019M661642).
Uncontrolled Keywords: titanium, silver, nanorod, antibacterial, biocompatibility
Subjects: A400 Clinical Dentistry
F200 Materials Science
Department: Faculties > Engineering and Environment > Mechanical and Construction Engineering
Depositing User: John Coen
Date Deposited: 28 Apr 2021 12:21
Last Modified: 26 Aug 2021 08:01
URI: http://nrl.northumbria.ac.uk/id/eprint/46044

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