Au@Ag@Pt core-shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility

Qiu, Jiajun, Yang, Tingting, Li, Yifan, Qian, Wenhao and Liu, Xuanyong (2021) Au@Ag@Pt core-shell nanorods regulating Ag release behavior endow titanium antibacterial activity and biocompatibility. Rare Metals. ISSN 1001-0521 (In Press)

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Abstract

Although titanium and its alloys are extensively used in orthopedics and dentistry fields, implant failures still happen because of implant-associated infections. Herein, Au@Ag@Pt core-shell nanorods with noble metal combination were fabricated and assembled on medical titanium surface and the antibacterial activity and biocompatibility were investigated. The results showed that antibacterial rates of Ti-Au@Ag@Pt against S. epidermidis and P. aeruginosa were 89.7% and 92.7%, respectively. Besides, Ti-Au@Ag@Pt showed no obvious cell toxicity with MC3T3-E1 cells grew well on the sample surface. It was discovered that the Pt shell layer on Ti-Au@Ag@Pt slowed down the Ag ion release rate which endowed medical titanium surface with both antibacterial activity and good biocompatibility.

Item Type: Article
Uncontrolled Keywords: titanium, silver, nanorod, antibacterial, biocompatibility
Subjects: A400 Clinical Dentistry
F200 Materials Science
Department: Faculties > Engineering and Environment > Mechanical and Construction Engineering
Depositing User: John Coen
Date Deposited: 28 Apr 2021 12:21
Last Modified: 28 Apr 2021 12:30
URI: http://nrl.northumbria.ac.uk/id/eprint/46044

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