Aerobic exercise intensity does not affect the anabolic signaling following resistance exercise in endurance athletes

Jones, Thomas, Eddens, L., Kupusarevic, Joe, Camargo Madeira Simoes, Davina, Furber, M. J. W., van Someren, K. A. and Howatson, Glyn (2021) Aerobic exercise intensity does not affect the anabolic signaling following resistance exercise in endurance athletes. Scientific Reports, 11 (1). p. 10785. ISSN 2045-2322

[img]
Preview
Text
s41598-021-90274-8.pdf - Published Version
Available under License Creative Commons Attribution 4.0.

Download (1MB) | Preview
Official URL: https://doi.org/10.1038/s41598-021-90274-8

Abstract

This study examined whether intensity of endurance stimulus within a concurrent training paradigm influenced the phosphorylation of signaling proteins associated with the mTOR and AMPK networks. Eight male cyclists completed (1) resistance exercise (RES), 6 × 8 squats at 80% 1-RM; (2) resistance exercise and moderate intensity cycling of 40 min at 65% V̇O2peak, (RES + MIC); (3) resistance exercise and high intensity interval cycling of 40 min with 6 alternating 3 min intervals of 85 and 45% V̇O2peak (RES + HIIC), in a cross-over design. Muscle biopsies were collected at rest and 3 h post-RES. There was a main effect of condition for mTORS2448 (p = 0.043), with a greater response in the RES + MIC relative to RES condition (p = 0.033). There was a main effect of condition for AMPKα2T172 (p = 0.041), with a greater response in RES + MIC, relative to both RES + HIIC (p = 0.026) and RES (p = 0.046). There were no other condition effects for the remaining protein kinases assessed (p > 0.05). These data do not support a molecular interference effect in cyclists under controlled conditions. There was no intensity-dependent regulation of AMPK, nor differential activation of anabolism with the manipulation of endurance exercise intensity.

Item Type: Article
Subjects: C600 Sports Science
Department: Faculties > Health and Life Sciences > Applied Sciences
Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: Elena Carlaw
Date Deposited: 25 May 2021 09:53
Last Modified: 31 May 2021 14:37
URI: http://nrl.northumbria.ac.uk/id/eprint/46269

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics