Associations between sleep parameters, non-communicable diseases, HIV status and medications in older, rural South Africans

Gómez-Olivé, F. Xavier, Rohr, Julia K., Roden, Laura C., Rae, Dale E. and von Schantz, Malcolm (2018) Associations between sleep parameters, non-communicable diseases, HIV status and medications in older, rural South Africans. Scientific Reports, 8 (1). p. 17321. ISSN 2045-2322

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As part of the Health and Aging in Africa: A Longitudinal Study of an INDEPTH Community in South Africa (HAALSI), we investigated sleep habits and their interactions with HIV or non-communicable diseases (NCDs) in 5059 participants (median age: 61, interquartile range: 52—71, 54 females). Self-reported sleep duration was 8.2 ± 1.6h, and bed and rise times were 20:48 ± 1:15 and 05:31 ± 1:05 respectively. Ratings of insufficient sleep were associated with older age, lack of formal education, unemployment, and obesity (p < 0.05). Ratings of restless sleep were associated with being older, female, having more education, being unemployed, and single. Hypertension was associated with shorter self-reported sleep duration, poor sleep quality, restless sleep, and periods of stopping breathing during the night (p < 0.05). HIV positive individuals not on antiretroviral treatment (ART) reported more nocturnal awakenings than those on ART (p = 0.029) and HIV negative individuals (p = 0.024), suggesting a negative net effect of untreated infection, but not of ART, on sleep quality. In this cohort, shorter, poor-quality sleep was associated with hypertension, but average self-reported sleep duration was longer than reported in other regions globally. It remains to be determined whether this is particular to this cohort, South Africa in general, or low- to middle-income countries undergoing transition.

Item Type: Article
Additional Information: The authors are very grateful to the Agincourt Community for their participation in this study. We would like to extend our sincere thanks to the MRC/Wits Agincourt Research Unit. This work has been possible thanks to the continuous effort of the field staff and data team who, with their zeal and dedication, guaranteed high quality data. Thanks also to the community engagement and administration teams, whose efforts are essential. The HAALSI study, funded by the National Institute on Aging (P01 AG041710), is nested within the Agincourt Health and Demographic Surveillance System site, supported by the University of the Witwatersrand and Medical Research Council, South Africa, and the Wellcome Trust, UK (grants 058893/Z/99/A; 069683/Z/02/Z; 085477/Z/08/Z; 085477/B/08/Z). The HAALSI study has been carried out through a collaboration between the Harvard Center for Population and Development Studies from the Harvard T.H. Chan School of Public Health, the MRC/Wits Rural Public Health and Health Transitions Research Unit from the School of Public Health at the University of the Witwatersrand in South Africa, and the INDEPTH Network in Accra, Ghana. The AWI-Gen Collaborative Centre is funded by the NIH (1U54HG006938) as part of the H3Africa Consortium. This collaboration was enabled by the National Research Foundation of South Africa’s UK/South Africa Researcher Links Grant (98108) to DER and MvS, and supported by a Newton Advanced Fellowship from the Academy of Medical Sciences to FXG-E and MvS.
Uncontrolled Keywords: South African, Self-reported Sleep Duration, Non-communicable Diseases (NCDs), Restless Sleep, Stopping Breathing
Subjects: B900 Others in Subjects allied to Medicine
Department: Faculties > Health and Life Sciences > Psychology
Depositing User: John Coen
Date Deposited: 27 Aug 2021 10:11
Last Modified: 27 Aug 2021 10:15

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