Items where Author is "Brown, Alistair"

Holt, Giles, Lodge, John, McCarthy, Alan, Graham, A. K., Young, Gregory, Bridge, Simon, Brown, Alistair, Veses-Garcia, M., Lanyon, Clare, Sails, A., Allison, Heather and Smith, Darren (2017) Shigatoxin encoding Bacteriophage φ24B modulates bacterial metabolism to raise antimicrobial tolerance. Scientific Reports, 7. p. 40424. ISSN 2045-2322

Scalacci, Nicolò, Brown, Alistair, Pavan, Fernando, Ribeiro, Camila, Manetti, Fabrizio, Bhakta, Sanjib, Maitra, Arundhati, Smith, Darren, Petricci, Elena and Castagnolo, Daniele (2017) Synthesis and SAR evaluation of novel thioridazine derivatives active against drug-resistant tuberculosis. European Journal of Medicinal Chemistry, 127. pp. 147-158. ISSN 0223-5234

Bhakta, Sanjib, Scalacci, Nicolò, Maitra, Arundhati, Brown, Alistair, Dasugari, Saiprasad, Evangelopoulos, Dimitrios, McHugh, Timothy, Mortazavi, Parisa, Twist, Alexander, Petricci, Elena, Manetti, Fabrizio and Castagnolo, Daniele (2016) Design and Synthesis of 1-((1,5-Bis(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)methyl)-4-methylpiperazine (BM212) and N-Adamantan-2-yl-N′-((E)-3,7-dimethylocta-2,6-dienyl)ethane-1,2-diamine (SQ109) Pyrrole Hybrid Derivatives: Discovery of Potent Antitubercular Agents Effective against Multidrug-Resistant Mycobacteria. Journal of Medicinal Chemistry, 59 (6). pp. 2780-2793. ISSN 0022-2623

Holt, Giles, Allison, Heather, Kinghan, S., McCarthy, Alan, Lodge, John, Brown, Alistair, Lanyon, Clare and Smith, Darren (2014) Stx-phage vB_EcoP 24B sculpting host bacterial function. In: Society for General Microbiology Annual Conference, 14 - 17 April 2014, Liverpool, UK.

Holt, Giles, Allison, Heather, Kinghan, S., McCarthy, Alan, Lodge, John, Brown, Alistair, Lanyon, Clare and Smith, Darren (2014) Stx-phage vB_EcoP 24B sculpting host bacterial function. In: Viruses of microbes: Structure and function, from molecules to communities, 14 - 18 July, 2014, Zurich, Switzerland.

Winther, Kristoffer, Brodersen, Ditlev, Brown, Alistair and Gerdes, Kenn (2013) VapC20 of Mycobacterium tuberculosis cleaves the Sarcin–Ricin loop of 23S rRNA. Nature Communications, 4. p. 2796. ISSN 2041-1723

Sutcliffe, Iain, Brown, Alistair and Dover, Lynn (2010) The rhodococcal cell envelope: composition, organisation and biosynthesis. In: Biology of Rhodococcus. Microbiology Monographs, 16 . Springer, London, pp. 29-71. ISBN 978-3642129360

Taylor, Rebecca, Brown, Alistair, Singh, Albel, Bhatt, Apoorva and Besra, Gurdyal (2010) Characterization of a -hydroxybutyryl-CoA dehydrogenase from Mycobacterium tuberculosis. Microbiology, 156 (7). pp. 1975-1982. ISSN 1350-0872

Brown, Alistair, Taylor, Rebecca, Bhatt, Apoorva, Futterer, Klaus and Besra, Gurdyal (2009) Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases. PLoS ONE, 4 (7). e6306. ISSN 1932-6203

Al-Balas, Qosay, Anthony, Nahoum, Al-Jaidi, Bilal, Alnimr, Amani, Abbott, Grainne, Brown, Alistair, Taylor, Rebecca, Besra, Gurdyal, McHugh, Timothy, Gillespie, Stephen, Johnston, Blair, Mackay, Simon and Coxon, Geoffrey (2009) Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis H37Rv and the β-Ketoacyl-ACP Synthase mtFabH. PLoS ONE, 4 (5). e5617. ISSN 1932-6203

Veyron-Churlet, Romain, Molle, Virginie, Taylor, Rebecca, Brown, Alistair, Besra, Gurdyal, Zanella-Cleon, Isabelle, Futterer, Klaus and Kremer, Laurent (2008) The mycobacterium tuberculosis beta-ketoacyl-acyl carrier protein synthase III activity is inhibited by phosphorylation on a single threonine residue. The Journal of Biological Chemistry, 284. pp. 6414-6424. ISSN 0021-9258

Bhowruth, Veemal, Alderwick, Luke, Brown, Alistair, Bhatt, Apoorva and Besra, Gurdyal (2008) Tuberculosis: a balanced diet of lipids and carbohydrates. Biochemical Society Transactions, 36 (4). pp. 555-565. ISSN 0300-5127

Dover, Lynn, Alderwick, Luke, Bhowruth, Veemal, Brown, Alistair, Kremer, Laurent and Besra, Gurdyal (2008) Antibiotics and new inhibitors of the cell envelope. In: The Mycobacterial Cell Envelope. American Society for Microbiology, Washington, DC, pp. 107-132. ISBN 978-1555814687

Mishra, Kanhu, de Chastellier, Chantal, Narayana, Yeddula, Bifani, Pablo, Brown, Alistair, Besra, Gurdyal, Katoch, Vishwa, Joshi, Beenu, Balaji, Kithiganahalli and Kremer, Laurent (2008) Functional role of the PE domain and immunogenicity of the mycobacterium tuberculosis triacylglycerol hydrolase lipY. Infection and Immunity, 76 (1). pp. 127-140. ISSN 0019-9567

Bhatt, Apoorva, Brown, Alistair, Singh, Albel, Minnikin, David and Besra, Gurdyal (2008) Loss of a mycobacterial gene encoding a reductase leads to an altered cell wall containing β-oxo- mycolic acid analogs and accumulation of ketones. Chemistry & Biology, 15 (9). pp. 930-939. ISSN 1074-5521

Bhowruth, Veemal, Brown, Alistair and Besra, Gurdyal (2008) Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636. Microbiology, 154 (7). pp. 1866-1875. ISSN 1350-0872

Sridharan, Sudharsan, Dover, Lynn, Brown, Alistair, Wang, Lei, Kremer, Laurent, Besra, Gurdyal and Sacchettini, James (2007) X-ray crystal structure of Mycobacterium tuberculosis beta-ketoacyl acyl carrier protein synthase II (mtKasB). Journal of Molecular Biology, 366 (2). pp. 469-480. ISSN 0022-2836