Items where Author is "Soundararajan, Meera"
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Article
Ciardullo, Carmela, Szoltysek, Katarzyna, Zhou, Peixun, Pietrowska, Monika, Marczak, Lukasz, Willmore, Elaine, Enshaei, Amir, Walaszczyk, Anna, Ho, Jia Yee, Rand, Vikki, Marshall, Scott, Hall, Andrew G., Harrison, Christine J., Soundararajan, Meera and Eswaran, Jeyanthy (2021) Low BACH2 Expression Predicts Adverse Outcome in Chronic Lymphocytic Leukaemia. Cancers, 14 (1). p. 23. ISSN 2072-6694
Szoltysek, Katarzyna, Ciardullo, Carmela, Zhou, Peixun, Walaszczyk, Anna, Willmore, Elaine, Rand, Vikki, Marshall, Scott, Hall, Andy, J. Harrison, Christine, Eswaran, Jeyanthy and Soundararajan, Meera (2020) DAP Kinase-Related Apoptosis-Inducing Protein Kinase 2 (DRAK2) Is a Key Regulator and Molecular Marker in Chronic Lymphocytic Leukemia. International Journal of Molecular Sciences, 21 (20). p. 7663. ISSN 1422-0067
Lewis, Frank, Fairooz, Safiya, Elson, Joanna L., Hubscher-Bruder, Véronique, Brandel, Jeremy, Soundararajan, Meera, Smith, David, Dexter, David T., Tétard, David and Pienaar, Ilse S. (2020) Novel 1-hydroxypyridin-2-one metal chelators prevent and rescue ubiquitin proteasomal-related neuronal injury in an in vitro model of Parkinson’s disease. Archives of Toxicology, 94 (3). pp. 813-831. ISSN 0340-5761
Lavinya, Amanda A., Razali, Ruzzieatul A., Razak, Munirah A., Mohamed, Rashidah, Moses, Emmanuel J., Soundararajan, Meera, Bruce, Lesley J, Eswaran, Jeyanthy and Yusoff, Narazah Mohd (2020) Homozygous Southeast Asian Ovalocytosis in five live-born neonates. Haematologica. ISSN 0390-6078
Zakaria, Zubaidah, Zulkifle, Muhamad Farid, Wan Hasan, Wan Atiqah Najiah, Azhari, Azlah Kamilah, Abdul Raub, Sayyidi Hamzi, Eswaran, Jeyanthy, Soundararajan, Meera and Syed Husain, Sharifah Noor Akmal (2019) Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort. OncoTargets and Therapy, Volume. pp. 7749-7756. ISSN 1178-6930
Kay, Laura, Sangal, Vartul, Black, Gary and Soundararajan, Meera (2019) Proteomics and bioinformatics analyses identify novel cellular roles outside mitochondrial function for human miro GTPases. Molecular and Cellular Biochemistry, 451 (1-2). pp. 21-35. ISSN 0300-8177
Peters, Daniel, Kay, Laura, Eswaran, Jeyanthy, Lakey, Jeremy and Soundararajan, Meera (2018) Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism. International Journal of Molecular Sciences, 19 (12). p. 3839. ISSN 1422-0067
Kay, Laura, Pienaar, Ilse, Cooray, Ruwini, Black, Gary and Soundararajan, Meera (2018) Understanding Miro GTPases: Implications in the Treatment of Neurodegenerative Disorders. Molecular Neurobiology, 55 (9). pp. 7352-7365. ISSN 0893-7648
Soundararajan, Meera, Roos, Annette, Savitsky, Pavel, Filippakopoulos, Panagis, Kettenbach, Arminja, Olsen, Jesper, Gerber, Scott, Eswaran, Jeyanthy, Knapp, Stefan and Elkins, Jonathan (2013) Structures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate Recognition. Structure, 21 (6). pp. 986-996. ISSN 0969-2126
Soundararajan, Meera and Eswaran, Jeyanthy (2012) Atypical GTPases as drug targets. Anti-cancer agents in medicinal chemistry, 12 (1). pp. 19-28. ISSN 1875-5992
Debdab, Mansour, Carreaux, François, Renault, Steven, Soundararajan, Meera, Fedorov, Oleg, Filippakopoulos, Panagis, Lozach, Olivier, Babault, Lucie, Tahtouh, Tania, Baratte, Blandine, Ogawa, Yasushi, Hagiwara, Masatoshi, Eisenreich, Andreas, Rauch, Ursula, Knapp, Stefan, Meijer, Laurent and Bazureau, Jean-Pierre (2011) Leucettines, a Class of Potent Inhibitors of cdc2-Like Kinases and Dual Specificity, Tyrosine Phosphorylation Regulated Kinases Derived from the Marine Sponge Leucettamine B: Modulation of Alternative Pre-RNA Splicing. Journal of Medicinal Chemistry, 54 (12). pp. 4172-4186. ISSN 0022-2623
Kwiatkowski, Nicholas, Jelluma, Nannette, Filippakopoulos, Panagis, Soundararajan, Meera, Manak, Michael, Kwon, Mijung, Choi, Hwan Geun, Sim, Taebo, Deveraux, Quinn, Rottmann, Sabine, Pellman, David, Shah, Jagesh, Kops, Geert, Knapp, Stefan and Gray, Nathanael (2010) Small-molecule kinase inhibitors provide insight into Mps1 cell cycle function. Nature Chemical Biology, 6 (5). pp. 359-368. ISSN 1552-4450
Kimple, Adam, Soundararajan, Meera, Hutsell, Stephanie, Roos, Annette, Urban, Daniel, Setola, Vincent, Temple, Brenda, Roth, Bryan, Knapp, Stefan, Willard, Francis and Siderovski, David (2009) Structural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2). Journal of Biological Chemistry, 284 (29). pp. 19402-19411. ISSN 0021-9258
Eswaran, Jeyanthy, Soundararajan, Meera and Knapp, Stefan (2009) Targeting group II PAKs in cancer and metastasis. Cancer and Metastasis Reviews, 28 (1-2). pp. 209-217. ISSN 0167-7659
Soundararajan, Meera, Willard, Francis, Kimple, Adam, Turnbull, Andrew P., Ball, Linda, Schoch, Guillaume, Gileadi, Carina, Fedorov, Oleg, Dowler, Elizabeth, Higman, Victoria, Hutsell, Stephanie, Sundstrom, Michael, Doyle, Declan A. and Siderovski, David (2008) Structural diversity in the RGS domain and its interaction with heterotrimeric G protein -subunits. Proceedings of the National Academy of Sciences of the United States of America, 105 (17). pp. 6457-6462. ISSN 0027-8424
Soundararajan, Meera, Turnbull, Andrew P., Fedorov, Oleg, Johansson, Catrine and Doyle, Declan A. (2008) RhoB can adopt a Mg2+ free conformation prior to GEF binding. Proteins: Structure, Function, and Bioinformatics, 72 (1). pp. 498-505. ISSN 0887-3585
Book Section
Kay, L. J., Smulders-Srinivasan, Tora and Soundararajan, Meera (2016) Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A. In: Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods. Elsevier, London, pp. 127-171. ISBN 978-0-12-804825-2
Conference or Workshop Item
Ciardullo, C., Zhou, Peng, Willmore, Elaine, Harrison, C. J., Hall, A., Eswaran, Jeyanthy and Soundararajan, Meera (2016) Impact of the apoptotic regulator DRAK2 in chronic lymphocytic leukemia. In: 36th World Congress of the International Society of Hematology, 18 - 21 April 2016, Glasgow.