Dynamic model of gene regulation for the lac operon

Angelova, Maia and Ben Halim, Asma (2011) Dynamic model of gene regulation for the lac operon. Journal of Physics: Conference Series, 286 (1). ISSN 1742-6596

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Official URL: http://dx.doi.org/10.1088/1742-6596/286/1/012007


Gene regulatory network is a collection of DNA which interact with each other and with other matter in the cell. The lac operon is an example of a relatively simple genetic network and is one of the best-studied structures in the Escherichia coli bacteria. In this work we consider a deterministic model of the lac operon with a noise term, representing the stochastic nature of the regulation. The model is written in terms of a system of simultaneous first order differential equations with delays. We investigate an analytical and numerical solution and analyse the range of values for the parameters corresponding to a stable solution.

Item Type: Article
Subjects: F300 Physics
Department: Faculties > Engineering and Environment > Mathematics, Physics and Electrical Engineering
Depositing User: EPrint Services
Date Deposited: 11 Aug 2011 12:04
Last Modified: 17 Dec 2023 11:35
URI: https://nrl.northumbria.ac.uk/id/eprint/103

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