Synthesis of β-Amino alcohols via the reduction of lactamides derived from Ethyl (2S)-Lactate with Borane-Methyl Sulfide

Lewis, Frank, Eichler, Matthias C. and Grayson, David (2009) Synthesis of β-Amino alcohols via the reduction of lactamides derived from Ethyl (2S)-Lactate with Borane-Methyl Sulfide. Synlett, 12. pp. 1923-1928. ISSN 0936-5214

PDF (Pre-print version)
Lactamides_Paper_1.pdf - Submitted Version
Restricted to Repository staff only
Download (907kB) | Request a copy

Official URL: http://dx.doi.org/10.1055/s-0029-1217538

Abstract

Reactions of ethyl (2S)-lactate with various amines affords lactamides that are reduced with borane-methyl sulfide in the presence of boron trifluoride etherate to generate enantiomerically pure β-amino alcohols in good yield.

Item Type:	Article
Subjects:	F100 Chemistry
Department:	Faculties > Health and Life Sciences > Applied Sciences
Depositing User:	Frank Lewis
Date Deposited:	21 Dec 2012 15:50
Last Modified:	01 Aug 2021 06:21
URI:	http://nrl.northumbria.ac.uk/id/eprint/10877

Actions (login required)

View Item

Downloads

Downloads per month over past year

View more statistics