Reduction of cholera in Bangladeshi villages by simple filtration

Colwell, Rita, Islam, M. Sirajul, Aziz, K. M. Ashraful, Huq, Anwar, Yunus, Mohammed, Khan, N. Huda, Mahmud, A., Sack, R. Bradley, Nair, G. Balakrish, Chakraborty, J., Sack, David and Russek-Cohen, Estelle (2003) Reduction of cholera in Bangladeshi villages by simple filtration. Proceedings of the National Academy of Sciences of the United States of America, 100 (3). pp. 1051-1055. ISSN 0027-8424

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Abstract

Based on results of ecological studies demonstrating that Vibrio cholerae, the etiological agent of epidemic cholera, is commensal to zooplankton, notably copepods, a simple filtration procedure was developed whereby zooplankton, most phytoplankton, and particulates >20 μm were removed from water before use. Effective deployment of this filtration procedure, from September 1999 through July 2002 in 65 villages of rural Bangladesh, of which the total population for the entire study comprised ≈133,000 individuals, yielded a 48% reduction in cholera (P < 0.005) compared with the control.

Item Type:	Article
Additional Information:	Senior Scientist and fieldwork lead in Bangladesh. Earlier discovery of the survival and toxigeneity of Vibrio cholerae 01 within phytoplankton by Islam M.S. led to rationale behind this low cost infectious intervention study. Gained global coverage through leading scientific bodies but also as a National Geographical Society feature
Subjects:	A900 Others in Medicine and Dentistry
Department:	Faculties > Engineering and Environment > Geography and Environmental Sciences
Depositing User:	EPrint Services
Date Deposited:	22 Dec 2008 15:12
Last Modified:	12 Oct 2019 22:52
URI:	http://nrl.northumbria.ac.uk/id/eprint/1356

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