Recent Applications of the Intramolecular Diels-Alder Furan (IMDAF) Reaction in Natural Product Synthesis

Lewis, Frank and Harwood, Laurence (2012) Recent Applications of the Intramolecular Diels-Alder Furan (IMDAF) Reaction in Natural Product Synthesis. In: Targets in Heterocyclic Systems. Royal Society of Chemistry/Italian Chemical Society, London, pp. 1-30. ISBN 978-8-88620-862-8

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Abstract

The intramolecular Diels-Alder furan (IMDAF) cycloaddition reaction is a versatile pericyclic
reaction for the regio- and stereoselective synthesis of 6-membered carbocyclic and heterocyclic rings. In
this chapter, recent applications of this reaction in organic synthesis are reviewed, with a particular
emphasis on its utility as a key step in the total synthesis of complex natural products

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