New insights into the distribution of WXG100 protein secretion systems

Sutcliffe, Iain (2011) New insights into the distribution of WXG100 protein secretion systems. Antonie van Leeuwenhoek, 99 (2). pp. 127-131. ISSN 0003-6072

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Abstract

Protein secretion is an important aspect of bacterial interaction with the environment. The WXG100 secretion system is a poorly understood pathway for the secretion of members of the WXG100 protein family in Firmicutes and Actinobacteria, notably Mycobacteria. This pathway has also been termed the Type VII secretion system but there are semantic problems with this nomenclature. This Perspective reviews the phylum level distribution of WXG100 secretion systems and presents comparative genomic evidence that these systems are present in several Chloroflexi and in some members of the phyla Cyanobacteria, Lentisphaerae, Proteobacteria (notably Helicobacter pylori) and Verrucomicrobiae. These findings have implications for the nomenclature of the WXG100 secretion pathway.

Item Type:	Article
Uncontrolled Keywords:	chloroflexus, comparative genomics, protein secretion, roseiflexus, type VII secretion
Subjects:	F100 Chemistry
Department:	Faculties > Health and Life Sciences > Applied Sciences
Related URLs:	Publisher
Depositing User:	EPrint Services
Date Deposited:	12 Oct 2011 10:59
Last Modified:	12 Oct 2019 18:26
URI:	http://nrl.northumbria.ac.uk/id/eprint/1730

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