The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays

Li, Yifan, McKenna, Ekaterina, Parkes, William, Pitt, Andrew and Walton, Anthony (2011) The application of fixed hydrophobic patterns for confinement of aqueous solutions in proteomic microarrays. Applied Physics Letters, 99 (7). 073703. ISSN 0003-6951

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Abstract

A protein microarray hybridisation system has been implemented by employing patterned hydrophobic thin films on hydrophilic substrates as a means of confinement for aqueous samples. This approach has the ability to handle, and keep separate, small sample volumes of just a few microlitres. In addition, the system is more straight forward to use than the existing multi-well gasket solution. The paper describes the fabrication method and the system is demonstrated for a model protein microarray assay.

Item Type:	Article
Subjects:	C900 Others in Biological Sciences F200 Materials Science F300 Physics
Department:	Faculties > Engineering and Environment > Mechanical and Construction Engineering
Depositing User:	Yifan Li
Date Deposited:	26 Feb 2015 14:34
Last Modified:	12 Oct 2019 22:52
URI:	http://nrl.northumbria.ac.uk/id/eprint/21227

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