Cellier, Marie, James, Arthur, Lowe, Jonathan, Orenga, Sylvain, Perry, John, Rasul, Ari and Stanforth, Stephen (2016) Detection of l-alanylaminopeptidase activity in microorganisms using fluorogenic self-immolative enzyme substrates. Bioorganic & Medicinal Chemistry, 24 (18). pp. 4066-4074. ISSN 0968 0896
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Official URL: http://dx.doi.org/10.1016/j.bmc.2016.06.051
Abstract
A series of fluorogenic enzymatic substrates that incorporate a self-immolative spacer were synthesised for the purpose of identifying l-alanylaminopeptidase activity in microorganisms in agar media. These substrates resulted in the generation of fluorescent microorganism colonies with Gram-negative microorganisms.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Fluorogenic enzyme substrates; l-Alanylaminopeptidase detection; Microorganisms |
| Subjects: | C500 Microbiology |
| Department: | Faculties > Health and Life Sciences > Applied Sciences |
| Depositing User: | Becky Skoyles |
| Date Deposited: | 07 Sep 2016 09:37 |
| Last Modified: | 01 Aug 2021 06:36 |
| URI: | http://nrl.northumbria.ac.uk/id/eprint/27652 |
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