Cholewinski, A. J., Stevens, G., McDermott, Alison and Wilkin, G. P. (1991) Identification of B2 Bradykinin Binding Sites on Cultured Cortical Astrocytes. Journal of Neurochemistry, 57 (4). pp. 1456-1458. ISSN 0022-3042
Full text not available from this repository. (Request a copy)Abstract
Bradykinin was found to bind to specific high-affinity sites in cultured cortical astrocytes from rat brain, and this binding appeared to be specific for the B2 bradykinin receptor subtype. Nonlinear regression analysis of saturation experiments using a computer programme revealed a single KD of 16.6 ± 2.6 nM and a Bmax of 352.2 ±30.7 fmol/mg of protein. These results indicate that astrocytes possess bradykinin receptors and that these are predominantly of the B2 subtype.
Item Type: | Article |
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Uncontrolled Keywords: | Bradykinin; Bradykinin receptors; Astrocytes; Cell culture |
Subjects: | C800 Psychology C900 Others in Biological Sciences |
Department: | Faculties > Health and Life Sciences > Applied Sciences |
Depositing User: | Becky Skoyles |
Date Deposited: | 25 May 2017 08:14 |
Last Modified: | 12 Oct 2019 17:29 |
URI: | http://nrl.northumbria.ac.uk/id/eprint/30850 |
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