Pulse mode operation of Love wave devices for biosensing applications

Newton, Michael, McHale, Glen, Martin, Fabrice, Gizeli, Electra and Melzak, Kathryn (2001) Pulse mode operation of Love wave devices for biosensing applications. Analyst, 126 (12). pp. 2107-2109. ISSN 0003-2654

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Official URL: https://doi.org/10.1039/b109259f


In this work we present a novel pulse mode Love wave biosensor that monitors both changes in amplitude and phase. A series of concentrations of 3350 molecular weight poly(ethylene glycol) (PEG) solutions are used as a calibration sequence for the pulse mode system using a network analyzer and high frequency oscilloscope. The operation of the pulse mode system is then compared to the continuous wave network analyzer by showing a sequence of deposition and removal of a model mass layer of palmitoyl-oleoyl-sn-glycerophosphocholine (POPC) vesicles. This experimental apparatus has the potential for making many hundreds of measurements a minute and so allowing the dynamics of fast interactions to be observed.

Item Type: Article
Subjects: F300 Physics
Department: Faculties > Engineering and Environment > Mathematics, Physics and Electrical Engineering
Depositing User: Becky Skoyles
Date Deposited: 09 Jun 2017 09:56
Last Modified: 12 Oct 2019 19:05
URI: http://nrl.northumbria.ac.uk/id/eprint/31011

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