Hemodynamic effects of high intensity interval training in COPD patients exhibiting exercise-induced dynamic hyperinflation

Nasis, Ioannis, Kortianou, Eleni, Vasilopoulou, Μaroula, Spetsioti, Stavroula, Louvaris, Zafeiris, Kaltsakas, Georgios, Davos, C. H., Zakynthinos, S., Koulouris, Nikolaos and Vogiatzis, Ioannis (2015) Hemodynamic effects of high intensity interval training in COPD patients exhibiting exercise-induced dynamic hyperinflation. Respiratory Physiology & Neurobiology, 217. pp. 8-16. ISSN 1569-9048

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Abstract

Dynamic hyperinflation (DH) has a significant adverse effect on cardiovascular function during exercise in COPD patients. COPD patients with (n = 25) and without (n = 11) exercise-induced DH undertook an incremental (IET) and a constant-load exercise test (CLET) sustained at 75% peak work (WRpeak) prior to and following an interval cycling exercise training regime (set at 100% WRpeak with 30-s work/30-s rest intervals) lasting for 12 weeks. Cardiac output (Q) was assessed by cardio-bio-impedance (PhysioFlow, enduro, PF-O7) to determine Q mean response time (QMRT) at onset (QMRTON) and offset (QMRTOFF) of CLET. Post-rehabilitation only those patients exhibiting exercise-induced DH demonstrated significant reductions in QMRTON (from 82.2 ± 4.3 to 61.7 ± 4.2 s) and QMRTOFF (from 80.5 ± 3.8 to 57.2 ± 4.9 s). These post-rehabilitation adaptations were associated with improvements in inspiratory capacity, thereby suggesting that mitigation of the degree of exercise-induced DH improves central hemodynamic responses in COPD patients.

Item Type:	Article
Uncontrolled Keywords:	Cardiac output, COPD, Pulmonary rehabilitation
Subjects:	B100 Anatomy, Physiology and Pathology C600 Sports Science
Department:	Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User:	Becky Skoyles
Date Deposited:	02 Mar 2018 10:31
Last Modified:	11 Oct 2019 21:47
URI:	http://nrl.northumbria.ac.uk/id/eprint/33558

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