Toscani, Anita, Risi, Caterina, Black, Gary, Brown, Nicola, Shaaban, Ali, Turner, Nicholas J. and Castagnolo, Daniele (2018) Monoamine Oxidase (MAO-N) Whole Cell Biocatalyzed Aromatization of 1,2,5,6-Tetrahydropyridines into Pyridines. ACS Catalysis, 8 (9). pp. 8781-8787. ISSN 2155-5435
|
Text
Toscanietal2018final.pdf - Accepted Version Download (996kB) | Preview |
Abstract
A sustainable MAO-N biocatalyzed process for the synthesis of pyridines from aliphatic tetrahydropyridines (THP) has been developed. Pyridine compounds were synthesized under mild reaction conditions and with high conversion, exploiting MAO-N whole cells as aromatizing biocatalysts. The kinetic profile of the whole cell biocatalytic transformation was finally investigated via in situ 19F NMR.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | aromatization; biocatalysis; in situ NMR; MAO-N; pyridine; tetrahydropyridine |
| Subjects: | F100 Chemistry |
| Department: | Faculties > Health and Life Sciences > Applied Sciences |
| Depositing User: | Becky Skoyles |
| Date Deposited: | 28 Nov 2018 08:51 |
| Last Modified: | 31 Jul 2021 12:03 |
| URI: | http://nrl.northumbria.ac.uk/id/eprint/36940 |
Actions (login required)
 |
View Item |
Downloads
Downloads per month over past year
