A comprehensive review on tyrosinase inhibitors

Zolghadri, Samaneh, Bahrami, Asieh, Hassan Khan, Mahmud Tareq, Munoz, Jose, Garcia-Molina, Francisco, Garcia-Canovas, F. and Saboury, Ali Akbar (2019) A comprehensive review on tyrosinase inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 34 (1). pp. 279-309. ISSN 1475-6366

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Official URL: https://doi.org/10.1080/14756366.2018.1545767


Tyrosinase is a multi-copper enzyme which is widely distributed in different organisms and plays an important role in the melanogenesis and enzymatic browning. Therefore, its inhibitors can be attractive in cosmetics and medicinal industries as depigmentation agents and also in food and agriculture industries as antibrowning compounds. For this purpose, many natural, semi-synthetic and synthetic inhibitors have been developed by different screening methods to date. This review has focused on the tyrosinase inhibitors discovered from all sources and biochemically characterised in the last four decades.

Item Type: Article
Uncontrolled Keywords: Tyrosinase, inhibitor, depigmentation agents, antibrowning compounds
Subjects: C500 Microbiology
Department: Faculties > Health and Life Sciences > Applied Sciences
Depositing User: Elena Carlaw
Date Deposited: 10 Jan 2019 12:32
Last Modified: 01 Aug 2021 07:34
URI: http://nrl.northumbria.ac.uk/id/eprint/37532

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