Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults

Reay, Jonathon, Scholey, Andrew and Kennedy, David (2010) Panax ginseng (G115) improves aspects of working memory performance and subjective ratings of calmness in healthy young adults. Human Psychopharmacology: Clinical and Experimental, 25 (6). pp. 462-471. ISSN 0885-6222

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Abstract

Objective - There is a lack of research into the cognitive and mood effects of repeated ginseng ingestion. The present study assessed the effects of Panax ginseng (G115) on subjective mood and aspects of ‘working’ memory processes, following a single dose and following sub-chronic (7 days) ingestion, in healthy volunteers.

Methods - A placebo-controlled, double-blind, randomised, crossover was utilised. Thirty volunteers (mean age 22.87 years; SD 4.01) received each treatment (200 mg; 400 mg; placebo) for 8 days, in a counter balanced order, with a 6-day wash-out period. Testing was on days 1 and 8 of each treatment period, at pre-dose, 1, 2.5 and 4 h post-dose.

Results - Results revealed dose-related treatment effects (p < 0.05). Two hundred milligrams slowed a fall in mood at 2.5 and 4 h on day 1 and at 1 and 4 h on day 8, but slowed responding on a mental arithmetic task across day 1 and at 1 and 2.5 h on day 8. The 400 mg dose also improved calmness (restricted 2.5 and 4 h on day 1) and improved mental arithmetic across days 1 and 8.

Conclusions - We found no evidence of additional benefits, nor attenuation of acute effects following repeated ingestion of Panax ginseng (G115).

Item Type:	Article
Uncontrolled Keywords:	Panax, Ginseng, G115, memory, acute, chronic
Subjects:	B900 Others in Subjects allied to Medicine C800 Psychology
Department:	Faculties > Health and Life Sciences > Psychology
Depositing User:	Ay Okpokam
Date Deposited:	19 Dec 2011 11:45
Last Modified:	12 Oct 2019 16:29
URI:	http://nrl.northumbria.ac.uk/id/eprint/4223

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