Gold-on-glass microwave split-ring resonators with PDMS microchannels for differential measurement in microfluidic sensing

Camli, B., Altinagac, E., Kizil, H., Torun, Hamdi, Dundar, G. and Yalcinkaya, A. D. (2020) Gold-on-glass microwave split-ring resonators with PDMS microchannels for differential measurement in microfluidic sensing. Biomicrofluidics, 14 (5). 054102. ISSN 1932-1058

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Abstract

This paper describes a microwave resonator incorporating microfluidic lab-on-chip sensor system capable of performing simultaneous differential measurement based sensing of liquid samples. The resonators are split-ring resonator shapes made of gold on glass substrates. Directly bonded on glass substrates are polydimethylsiloxane microchannels. Sensor system design incorporates a pair of identical resonators, one of which performs reference reading from the background. Tracking the difference of the responses of both resonators simultaneously, rather than a single one, is used to obtain a more linear and noise-free reading. The sensor system was produced with conventional fabrication techniques. It is compatible with low-cost, simple, easy to handle sensing applications. Results indicate that reliable differential measurement was possible owing to a well-matched pair of sensors with a response error as low as 0.1%. It was also demonstrated that differential measurement capability enables sensing with improved linearity. Measurements were performed with glucose solutions in the range of 3.2–16.1 mM, achieving a sensitivity of 0.16 MHz/mM.

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