Long COVID-19 Pulmonary Sequelae and Management Considerations

Boutou, Afroditi K., Asimakos, Andreas, Kortianou, Eleni, Vogiatzis, Ioannis and Tzouvelekis, Argyris (2021) Long COVID-19 Pulmonary Sequelae and Management Considerations. Journal of Personalized Medicine, 11 (9). p. 838. ISSN 2075-4426

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Official URL: https://doi.org/10.3390/jpm11090838


The human coronavirus 2019 disease (COVID-19) and the associated acute respiratory distress syndrome (ARDS) are responsible for the worst global health crisis of the last century. Similarly, to previous coronaviruses leading to past pandemics, including severe acute respiratory syndrome (SARS) and middle east respiratory syndrome (MERS), a growing body of evidence support that a substantial minority of patients surviving the acute phase of the disease present with long-term sequelae lasting for up to 6 months following acute infection. The clinical spectrum of these manifestations is widespread across multiple organs and consists of the long-COVID-19 syndrome. The aim of the current review is to summarize the current state of knowledge on the pulmonary manifestations of the long COVID-19 syndrome including clinical symptoms, parenchymal, and functional abnormalities, as well as highlight epidemiology, risk factors, and follow-up strategies for early identification and timely therapeutic interventions. The literature data on management considerations including the role of corticosteroids and antifibrotic treatment, as well as the therapeutic potential of a structured and personalized pulmonary rehabilitation program are detailed and discussed.

Item Type: Article
Uncontrolled Keywords: Post-COVID sequelae, parenchymal abnormalities, functional limitation, rehabilitation
Subjects: B100 Anatomy, Physiology and Pathology
B900 Others in Subjects allied to Medicine
Department: Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: Rachel Branson
Date Deposited: 31 Aug 2021 11:15
Last Modified: 31 Aug 2021 11:15
URI: http://nrl.northumbria.ac.uk/id/eprint/47030

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