Isomaltulose improves glycaemia and maintains run performance in Type 1 Diabetes

Bracken, Richard, Page, Rhydian, Gray, Ben, Kilduff, Liam, West, Dan, Stephens, Jeffrey and Bain, Stephen (2012) Isomaltulose improves glycaemia and maintains run performance in Type 1 Diabetes. Medicine & Science in Sports & Exercise, 44 (5). pp. 800-808. ISSN 0195-9131

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Individuals with type 1 diabetes (T1DM) are encouraged to reduce rapid-acting insulin and consume carbohydrates to prevent hypoglycemia during or after exercise. However, research comparing the metabolic and performance effects of different carbohydrates is limited. This study compared the alterations in metabolism and fuel oxidation in response to performance running following pre-exercise ingestion of isomaltulose or dextrose in T1DM.

Following preliminary testing, on two occasions seven T1DM individuals consumed 0.6 body mass of either dextrose (DEX; GI 96), or isomaltulose (ISO; GI 32), two hours before a discontinuous, incremental run to 80 %VO2peak on a motorised treadmill followed by a 10 minute all-out performance test on a non-motorised treadmill. Blood glucose (BG), acid-base and cardio-respiratory parameters were measured for 2 hours before, during and after both run tests. Data (mean +/- SEM) were analysed using repeated-measures ANOVA.

Pre-exercise BGAUC was lower under ISO in comparison with DEX (ISO +4.0 +/- 0.3 vs. DEX +7.0 +/- 0.6 mmol.l-1.hour-1, P<0.01). Resting blood lactate concentrations and rate of carbohydrate oxidation under ISO were greater than those elicited under DEX (P<0.05). There were no metabolic or cardio-respiratory differences between conditions in response to submaximal exercise in spite of lower blood glucose concentrations under ISO (P<0.05). T1DM individuals completed the same distance at the same speed over the 10 minute run test under both conditions (NS).

Consumption of isomaltulose alongside rapid-acting insulin reduction improves blood glucose responses to exercise and produces a similar high-intensity run performance compared with dextrose in T1DM individuals.

Item Type: Article
Uncontrolled Keywords: blood glucose, fuel oxidation, carbohydrate, feeding, glycemic index
Subjects: A300 Clinical Medicine
C600 Sports Science
Department: Faculties > Health and Life Sciences > Sport, Exercise and Rehabilitation
Depositing User: Ay Okpokam
Date Deposited: 28 Feb 2012 14:51
Last Modified: 12 Oct 2019 15:29

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