Surface free energy and microarray deposition technology

McHale, Glen (2007) Surface free energy and microarray deposition technology. Analyst, 132 (3). pp. 192-195. ISSN 0003-2654

PDF (Postprint)
Postprint_McHale_Analyst_vol_132_p192_2007.pdf - Published Version

Download (254kB) | Preview
Official URL:


Microarray techniques use a combinatorial approach to assess complex biochemical interactions. The fundamental goal is simultaneous, large-scale experimentation analogous to the automation achieved in the semiconductor industry. However, microarray deposition inherently involves liquids contacting solid substrates. Liquid droplet shapes are determined by surface and interfacial tension forces, and flows during drying. This article looks at how surface free energy and wetting considerations may influence the accuracy and reliability of spotted microarray experiments.

Item Type: Article
Uncontrolled Keywords: droplets, wetting, microarray,contact angle
Subjects: C100 Biology
F100 Chemistry
F300 Physics
Department: Faculties > Engineering and Environment > Mathematics, Physics and Electrical Engineering
Depositing User: Glen McHale
Date Deposited: 23 Aug 2012 11:58
Last Modified: 17 Dec 2023 12:48

Actions (login required)

View Item View Item


Downloads per month over past year

View more statistics